Print Icon
 
LAB BOOK Newsletter

APPLICATION NOTES

ebolavirus

Virus Specimen Preparation in Biosafety Level 3-4 Laboratories

This application note describes the negative stain TEM preparation of pathogenic Ebola virus in high containment BSL4 labs. Scientists from US Army Medical Research Institute of Infectious Diseases (USAMRIID) used mPrep™/g capsules to eliminate grid handling in the BSL suite, resulting in easier, safer processing and more reproducible sample preparation.
DNA-RecA

Negative Staining of Macromolecular Specimen for TEM

This application note illustrates the preparation of macromolecular specimens for negative stain TEM using mPrep™/g capsules. The example is a DNA-RecA complex, although the protocol is applicable to many other specimens.

PUBLICATION  |  DIGITAL MEDIA

Blancett, C.D. et al. J Vis Exp. 2017; (125): 56122

Authors describe a technique designed specifically for use in BSL-3 or -4 biocontainment to ease sample preparation in any lab environment by enabling easy negative staining of virus. This same method can also be applied to prepare negative stained TEM specimens of nanoparticles, macromolecules and similar specimens.

EVENTS

CANCELLED

Due to COVID-19, several microscopy meetings have been cancelled or postponed. Those we are aware of include:

Microscopy Innovations LLC

Creating 21st Century EM Lab Products to Accelerate Science

213 Air Park Road, Suite 101, Marshfield, WI 54449

Phone +1 715-384-3292 | www.MicroscopyInnovations.com | info@microscopyinnovations.com


© 2020 Microscopy Innovations LLC. Microscopy Innovations, the Microscopy Innovations logo and all other trademarks unless otherwise indicated are property of Microscopy Innovations LLC.